PLK1-IN-9, CAS 893772-67-3

Product Description: PLK1-IN-9 (Compound M2) is an inhibitor for polo-like kinase 1 (PLK1), that inhibits PLK proteins modified with peptides 1010pT, cdc25c and PBIP, with IC50s of 1.6, 0.8 and 1.4 μM, respectively. PLK1-IN-9 inhibits proliferations of cancer cells HeLa, HL60, SNU387/499, HepG2, exhibits cytotoxicity and induces apoptosis. PLK1-IN-9 inhibits tumor growth in HepG2 xenograft mouse model[1].

Formula: C12H7F3N4O2

References: [1]Kin K, et al., Pharmaceutical composition for preventing or treating cancer, containing activation inhibitor of plk1 as active ingredient. WO2020111325.

CAS Number: 893772-67-3

Molecular Weight: 296.20

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Polo-like Kinase (PLK)

• Artikelnummer: MEXHY-W276819-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W276819-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK