Description: PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor.
CAS Number: 1303420-67-8
Formula: C21H19F2N5O
Molecular Weight: 395,41
References: Rosin JM, Vora SR, Kurrasch DM.Depletion of embryonic microglia using the CSF1R inhibitor PLX5622 has adverse sex-specific effects on mice, including accelerated weight gain, hyperactivity and anxiolytic-like behaviour[J].Brain Behav Immun. 2018 Oct;73:682-697.