Pretomanid (Standard), CAS 187235-37-6

Product Description: Pretomanid (Standard) is the analytical standard of Pretomanid. This product is intended for research and analytical applications. Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

Formula: N/A

References: [1]Stover CK, et al. A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis. Nature. 2000 Jun 22;405(6789):962-6./[2]Lenaerts AJ, et al. Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models. Antimicrob Agents Chemother. 2005 Jun;49(6):2294-301./[3]Manjunatha UH, et al. Mycobacterium leprae is naturally resistant to PA-824. Antimicrob Agents Chemother. 2006 Oct;50(10):3350-4.

CAS Number: 187235-37-6

Molecular Weight: N/A

Research Area: Infection; Cancer

Target: Antibiotic;Bacterial

• Artikelnummer: MEXHY-10844R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-10844R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK