PROTAC NAMPT Degrader-1

Product Description: PROTAC NAMPT Degrader-1 is a potent PROTAC targeting NAMPT with aDC50 value of 217 nM. PROTAC NAMPT Degrader-1 has anti-proliferative activity with an IC50 value of 0.12μM against A2780 cells. (Srtucture Note: PINK, NAMPT activator (HY-163445); Blue, VHL ligand (HY-163440); Black, linker)[1].

Formula: C57H69N13O8S2

References: [1]Cheng J, et al. Photoswitchable PROTACs for Reversible and Spatiotemporal Regulation of NAMPT and NAD. Angew Chem Int Ed Engl. 2024 Mar 18;63(12):e202315997.

Molecular Weight: 1128.37

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: NAMPT;PROTACs

• Artikelnummer: MEXHY-163440-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-163440-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK