Rasagiline (mesylate) (Standard), CAS 161735-79-1

Rasagiline (mesylate) (Standard), CAS 161735-79-1
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MEXHY-14605R-0
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MedChemExpress

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Product Description: Rasagiline (mesylate) (Standard) is the analytical standard of Rasagiline (mesylate). This product is intended for research and analytical applications. Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively[1]. Rasagiline (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Formula: N/A

References: [1]M B Youdim, et al. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol. 2001 Jan;132(2):500-6./[2]Nadia Stefanova, et al. Rasagiline is neuroprotective in a transgenic model of multiple system atrophy. Exp Neurol. 2008 Apr;210(2):421-7./[3]Shawna Tazik, et al. Comparative neuroprotective effects of Rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis. Neurotox Res. 2009 Apr;15(3):284-90.

CAS Number: 161735-79-1

Molecular Weight: N/A

Research Area: Neurological Disease

Target: Apoptosis;Autophagy;Monoamine Oxidase
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Artikelnummer MEXHY-14605R-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-14605R-0
Green Labware Nein
Verpackungseinheit Get quote
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