Product Description: RK-287107 is a potent and specific tankyrase inhibitor with IC50s of 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively. RK-287107 blocks colorectal cancer cell growth[1].
Applications: Cancer-programmed cell death
Formula: C22H26F2N4O2
References: [1]Mizutani A, et al. RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model. Cancer Sci. 2018 Dec;109(12):4003-4014.
CAS Number: 2171386-10-8
Molecular Weight: 416.46
Compound Purity: 99.81
Research Area: Cancer
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: PARP