Ro15-4513, CAS 91917-65-6

Product Description: Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR)[1]. Ro15-4513 is a potent ethanol antagonist[2]. Ro15-4513 has anti-anxiety effect[3]. Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Neuroscience-Neuromodulation

Formula: C15H14N6O3

References: [1]Bonetti EP, et al. Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol. Pharmacol Biochem Behav. 1988 Nov;31(3):733-49./[2]Suzdak PD, et al. Effects of Ro15-4513 and other benzodiazepine receptor inverse agonists on alcohol-inducedintoxication in the rat. J Pharmacol Exp Ther. 1988 Jun;245(3):880-6./[3]Linden AM, et al. Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors. Front Neurosci. 2011 Jan 20;5:3.

CAS Number: 91917-65-6

Molecular Weight: 326.31

Compound Purity: 99.17

Research Area: Neurological Disease

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: GABA Receptor

• Artikelnummer: MEXHY-103476-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-103476-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK