Rolipram (Standard), CAS 61413-54-5

Product Description: Rolipram (Standard) is the analytical standard of Rolipram. This product is intended for research and analytical applications. Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC50s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.

Formula: N/A

References: [1]MacKenzie SJ, et al. Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocyticcells. Biochem J. 2000 Apr/[2]Korhonen R, et al. Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1. Br J Pharmacol. 2013 Aug;169(7):1525-36./[3]Shalaby AM, et al. Effect of rolipram, a phosphodiesterase enzyme type-4 inhibitor, on γ-amino butyric acid content of the frontal cortex in mice exposed to chronic mild stress. J Pharmacol Pharmacother. 2012 Apr;3(2):132-7.

CAS Number: 61413-54-5

Molecular Weight: N/A

Research Area: Neurological Disease; Cancer

Target: Bacterial;HIV;Phosphodiesterase (PDE)

• Artikelnummer: MEXHY-16900R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-16900R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK