Product Description: Rovanersen sodium is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen sodium can be used for huntington’s disease research[1].
Applications: Neuroscience-Neurodegeneration
Formula: C202H240N82Na19O111P19S13
References: [1]M Meena, et al. Selectivity and Biodistribution of WVE-120101, a Potential Antisense Oligonucleotide Therapy for the Treatment of Huntington’s Disease (S56.001). AAN Enterprises. April 18, 2017; 88 (16 Supplement).
CAS Number: 2231347-41-2
Molecular Weight: 7034.70
Research Area: Neurological Disease
Solubility: 10 mM in H2O
Target: Huntingtin