(S)-CR8, CAS 1084893-56-0

Product Description: (S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC50s of 0.060, 0.080, 0.11, 0.12, and 0.15 μM for CDK2/cyclin E, CDK2/cyclin A, CDK9/cyclin T, CDK5/p25, and CDK1/cyclin B, respectively. (S)-CR8 reduces SH-SY5Y cells survival (IC50 0.40 μM)[1].

Applications: Cancer-Kinase/protease

Formula: C24H29N7O

References: [1]K Bettayeb, et al. CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases. Oncogene. 2008 Oct 2;27(44):5797-807.

CAS Number: 1084893-56-0

Molecular Weight: 431.53

Compound Purity: 99.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: CDK

• Artikelnummer: MEXHY-112371-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-112371-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK