(S)-(+)-Ibuprofen (Standard), CAS 51146-56-6

Product Description: (S)-(+)-Ibuprofen (Standard) is the analytical standard of (S)-(+)-Ibuprofen. This product is intended for research and analytical applications. (S)-(+)-Ibuprofen ((S)-Ibuprofen), a S(+)-enantiomer of Ibuprofen, is a potent COX-1 and COX-2 inhibitor with IC50s of 2.1 μM and 1.6 μM, respectively. (S)-(+)-Ibuprofen has analgesic, anti-inflammatory, anticancer and antipyretic effects[1][2].

Formula: N/A

References: [1]Evans AM, et al. Comparative pharmacology of S(+)-ibuprofen and (RS)-ibuprofen. Clin Rheumatol. 2001 Nov;20 Suppl 1:S9-14./[2]N Scheuren, et al. Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen. Br J Pharmacol. 1998 Feb;123(4):645-52./[3]Astrid Janssen, et al. Evidence of COX-2 independent induction of apoptosis and cell cycle block in human colon carcinoma cells after S- or R-ibuprofen treatment. Eur J Pharmacol. 2006 Jul 1;540(1-3):24-33.

CAS Number: 51146-56-6

Molecular Weight: N/A

Research Area: Inflammation/Immunology

Target: COX

• Artikelnummer: MEXHY-78131AR-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-78131AR-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK