(S,R,S)-AHPC-Me-piperazine-acetyl-PIP-AcOH

Product Description: (S,R,S)-AHPC-Me-piperazine-acetyl-PIP-AcOH is a conjugate of the VHL ligand and linker of the E3 ubiquitinase VH032. The Linker of (S,R,S)-AHPC-Me-piperazine-acetyl-PIP-AcOH can further be linked to target protein ligands (such as BCR-ABL1) to form PROTAC molecules[1].

Formula: C35H52N8O5S

References: [1]Burslem GM, et al. Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-mediated Targeted Protein Degradation. Cancer Res. 2019 Jul 16. pii: canres. 1236. 2019

Molecular Weight: 696.90

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: E3 Ligase Ligand-Linker Conjugates

• Artikelnummer: MEXHY-161445-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161445-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK