SC912

Product Description: SC912 is an AR-V7 inhibitor (IC50 = 0.36 μM). SC912 possesses safety, potency and selectivity. SC912 binds directly to AR-FL and AR-V7 proteins, inhibites nuclear localization and chromatin binding capabilities. SC912 exerts anticancer activity through inhibition of proliferation, induction of cell cycle arrest and apoptosis[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C22H13Cl2F3N4O2

References: [1]Qianhui Y et al. SC912 inhibits AR-V7 activity in castration-resistant prostate cancer by targeting the androgen receptor N-terminal domain Oncogene. 2024 Mar

Molecular Weight: 493.27

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Androgen Receptor;Apoptosis

• Artikelnummer: MEXHY-161409-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161409-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK