SKLB-163, CAS 1255099-06-9

Product Description: SKLB-163 is an orally active inhibitor for Rho GDP-dissociation (RhoGDI). SKLB-163 inhibits highly expressed RhoGDI tumor cell proliferation and migration, and increases radiosensitivity of tumor cells. SKLB-163 induces cancer cell Apoptosis[1][2].

Formula: C18H16ClN3O2S2

References: [1]He J, et al. Antitumor and radiosensitizing effects of SKLB-163, a novel benzothiazole-2-thiol derivative, on nasopharyngeal carcinoma by affecting the RhoGDI/JNK-1 signaling pathway. Radiother Oncol. 2018 Oct;129(1):30-37./[2]Peng X,et al. SKLB-163, a new benzothiazole-2-thiol derivative, exhibits potent anticancer activity by affecting RhoGDI/JNK-1 signaling pathway. Cell Death Dis. 2014 Mar 27;5(3):e1143.

CAS Number: 1255099-06-9

Molecular Weight: 405.92

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis

• Artikelnummer: MEXHY-120429-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-120429-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK