Sodium Salicylate (Standard), CAS 54-21-7

Product Description: Sodium Salicylate (Standard) is the analytical standard of Sodium Salicylate. This product is intended for research and analytical applications. Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1]. Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle[4].

Formula: N/A

References: [1]Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12./[2]Nixon M, et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6./[3]Dongmei Bai, et al. Palmitic acid negatively regulates tumor suppressor PTEN through T366 phosphorylation and protein degradation. Cancer Lett. 2020 Oct 8;S0304-3835(20)30506-1./[4]Juhyun Oh, et al. Age-associated NF-κB signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function. Aging (Albany NY). 2016 Nov; 8(11): 2871–2884.

CAS Number: 54-21-7

Molecular Weight: N/A

Research Area: Cancer; Inflammation/Immunology

Target: Apoptosis;Autophagy;COX;Endogenous Metabolite;NF-κB;Ribosomal S6 Kinase (RSK)

• Artikelnummer: MEXHY-B0167AR-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0167AR-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK