Product Description: SOS1 Ligand intermediate-5 is the ligand for son of sevenless 1 (SOS1). SOS1 Ligand intermediate-5 is utilized for synthesis of PROTAC SOS1 degrader-10 (HY-161654)[1].
Formula: C24H26F3N5O3
References: [1]Wang, K, et al. “Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor.” Bioorganic & medicinal chemistry letters vol. 107 (2024): 129780.
Molecular Weight: 489.49
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Ligands for Target Protein for PROTAC