Product Description: ST166 free base is a inhibitor of formation of the PhoP-DNA complex with the IC50 values of 18 and 24 μM against PhoP and MtrAC binding with DNA, respectively. ST166 free base shows antibacterial activity against Macrobacterium marinum[1].
Formula: C6H12O6S6
References: [1]Su HL, Lai SJ, et al. Structure-guided identification and characterization of potent inhibitors targeting PhoP and MtrA to combat mycobacteria. Comput Struct Biotechnol J. 2024;23:1477-1488. Published 2024 Apr 3.