Sucrosofate (potassium), CAS 73264-44-5

Product Description: Sucrosofate (Sucrose octasulfate) potassium is a sucrose acid that can be used to prepare liposomes to deliver Irinotecan (HY-16562). Irinotecan is an inhibitor of topoisomerase Topo I and is commonly used in colon and rectal cancer research. Sucrosofate nanoliposome preparation loaded with Irinotecan, also known as PEP02 or MM-398[1][2].

Formula: C12H14K8O35S8

References: [1]Klinz S G, Zheng J, De Souza R, et al. Abstract C293: Irinotecan sucrosofate liposome injection, MM-398, demonstrates superior activity and control of hypoxia as measured through longitudinal imaging using [18F] FAZA PET compared to free irinotecan in a colon adenocarcinoma xenograft model[J]. Molecular Cancer Therapeutics, 2013, 12(11_Supplement): C293-C293./[2]Ko A H, Tempero M A, Shan Y S, et al. A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer[J]. British journal of cancer, 2013, 109(4): 920-925.

CAS Number: 73264-44-5

Molecular Weight: 1287.52

Research Area: cancer

Solubility: 10 mM in DMSO

Target: Biochemical Assay Reagents

• Artikelnummer: MEXHY-141436-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-141436-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK