T-Cadinol, CAS 5937-11-1

Product Description: T-Cadinol is a sesquiterpene isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity, with IC50 values of 18.2 μM and 15.8 μM against trypomastigote and amastigote forms, respectively. T-Cadinol can induce mitochondrial damage in parasites, leading to membrane hyperpolarization and decreased levels of reactive oxygen species. T-Cadinol can be used for the research of Chagas disease[1].

Formula: C15H26O

References: [1]Dos Santos AL, et al. (-)-T-Cadinol-a Sesquiterpene Isolated From <i>Casearia sylvestris</i> (Salicaceae)-Displayed <i>In Vitro</i> Activity and Causes Hyperpolarization of the Membrane Potential of <i>Trypanosoma cruzi</i> [published correction appears in Front Pharmacol. 2022 Mar 14;13:865432]. Front Pharmacol. 2021;12:734127. Published 2021 Nov 3.

CAS Number: 5937-11-1

Molecular Weight: 222.37

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Parasite

• Artikelnummer: MEXHY-N12788-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-N12788-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK