Description: Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
CAS Number: 1207456-01-6
Formula: C19H14F2N6O
Molecular Weight: 380,35
References: Wilkerson PM, et al. Preclinical evaluation of the PARP inhibitor BMN-673 for the treatment of ovarian clear cell cancer. Oncotarget. 2017 Jan 24;8(4):6057-6066.