TAT-CBD3A6K, CAS 1505463-57-9

Product Description: TAT-CBD3A6K, is a modified TAT-CBD3 peptide. TAT-CBD3A6K reduces T- and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. TAT-CBD3A6K shows anti-nociceptive effects in a model of AIDS-induced peripheral neuropathy by preventing CRMP-2-mediated enhancement of T- and R-type calcium channel function[1][2].

Formula: C137H250N60O32

References: [1]Piekarz AD, et al. CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy. Mol Pain. 2012 Jul 24;8:54./[2]Meloni BP, et al. Neuroprotective peptides fused to arginine-rich cell penetrating peptides: Neuroprotective mechanism likely mediated by peptide endocytic properties. Pharmacol Ther. 2015 Sep;153:36-54.

CAS Number: 1505463-57-9

Molecular Weight: 3249.83

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Calcium Channel

• Artikelnummer: MEXHY-P10358-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P10358-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK