Product Description: TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G[1] phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex[1].
Formula: C159H274N64O40
References: [1]Gius DR, et al. Transduced p16INK4a peptides inhibit hypophosphorylation of the retinoblastoma protein and cell cycle progression prior to activation of Cdk2 complexes in late G1. Cancer Res. 1999 Jun 1;59(11):2577-80.