TD1092

Product Description: TD1092 is a pan-IAP degrader, degrades cIAP1, cIAP2, and XIAP. TD1092 activates Caspase 3/7, and promotes cancer cells apoptosis via IAP degradation. TD1092 inhibits TNFα mediated NF-κB pathway and reduces the phosphorylation of IKK, IkBα, p65, and p38. TD1092 can act as PROTAC, and is used for cancer research[1].

Applications: Cancer-programmed cell death

Formula: C55H70N8O9

References: [1]Park S, et al. Discovery of pan-IAP degraders via a CRBN recruiting mechanism. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114910.

Molecular Weight: 987.19

Compound Purity: 99.49

Research Area: Cancer

Solubility: DMSO : ≥ 100 mg/mL

Target: Caspase;IAP;PROTACs

• Artikelnummer: MEXHY-151966-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-151966-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK