Product Description: TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research[1].
Formula: C15H14F3NO
References: [1]Henry William, et al. Yap/taz-tead oncoproteins inhibitors.WO2024059317A1.2023-09-15