TGX-115, CAS 351071-62-0

Product Description: TGX-115 is a cytopermeable and potent PI3-K isomer p110β/p110δ inhibitor (p110β IC50 value of 0.13 μM, p110δ IC50 value of 0.63 μM).TGX-115 is an enzyme that regulates platelet adhesion process and inhibits phosphoinosine 3-kinase. TGX-115 can be used in the study of cardiovascular diseases such as coronary artery occlusion, stroke, acute coronary syndrome, acute myocardial infarction, restenosis, arteriosclerosis and unstable angina[1].

Formula: C20H20N2O3

References: [1]Popovici-Muller J, et al. Discovery of AG-120 (Ivosidenib): a first-in-class mutant IDH1 inhibitor for the treatment of IDH1 mutant cancers[J]. ACS medicinal chemistry letters, 2018, 9(4): 300-305.

CAS Number: 351071-62-0

Molecular Weight: 336.38

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: PI3K

• Artikelnummer: MEXHY-124535-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-124535-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK