Thalidomide-benzylamine-Py-NH2

Product Description: Thalidomide-benzylamine-Py-NH2 is a conjugate of E3 ligase ligand and linker, which is consisted of a Thalidomide (HY-14658) and the Linker Boc-NHCH2-Ph-Py-NH2 (HY-161496). Thalidomide-benzylamine-Py-NH2 is utilized for synthesis of PROTAC molecule XYD190 (HY-161494)[1].

Applications: Cancer-programmed cell death

Formula: C25H21N5O4

References: [1]Hu J, et al., Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity. J Med Chem. 2024 May 9;67(9):6952-6986. 

Molecular Weight: 455.47

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: E3 Ligase Ligand-Linker Conjugates

• Artikelnummer: MEXHY-161497-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-161497-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK