Thalidomide-NH-C10-COOH, CAS 2428400-33-1

Product Description: Thalidomide-NH-C10-COOH (compound 6b) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology[1].

Applications: Cancer-programmed cell death

Formula: C24H31N3O6

References: [1]Kim K, et al. Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci Rep. 2019 Dec 23;9(1):19654.

CAS Number: 2428400-33-1

Molecular Weight: 457.52

Compound Purity: 97.50

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;E3 Ligase Ligand-Linker Conjugates

• Artikelnummer: MEXHY-130716-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-130716-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK