Product Description: Thalidomide-NH-PEG2-C2-CH2 is a conjugate of E3 ligase ligand and linker. Thalidomide-NH-PEG2-C2-CH2 is utilized for synthesis of PROTAC TEAD degrader-1 (HY-158342)[1].
Formula: C19H24N4O6
References: [1]Li H, et al., Design, Synthesis, and Bioevaluation of Transcriptional Enhanced Assocciated Domain (TEAD) PROTAC Degraders. ACS Med Chem Lett. 2024 Apr 22;15(5):631-639.
CAS Number: 2064175-30-8
Molecular Weight: 404.42
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: E3 Ligase Ligand-Linker Conjugates