Tilorone, CAS 27591-97-5

Product Description: Tilorone is an orally active antiviral agent and interferon inducer that also has potential antineoplastic, immunomodulatory, and metabolic modulating effects. Tilorone induces an abnormally delayed interferon response and primarily stimulates interferon production in lymphoid tissue. Thus, Tilorone exerts antiviral effects and can be used as a chemotherapeutic agent. Tilorone has the potential to inhibit type 2 diabetes by increasing glucose uptake in vivo and in skeletal muscle cells by enhancing Akt2/AS160 signaling and glucose transporter levels[1][2][3][4][5].

Formula: C25H34N2O3

References: [1]Ekins S, et al. Efficacy of tilorone dihydrochloride against Ebola virus infection[J]. Antimicrobial agents and chemotherapy, 2018, 62(2): 10.1128/aac. 01711-17./[2]Stringfellow D A, et al. Tilorone hydrochloride: an oral interferon-inducing agent[J]. Antimicrobial agents and chemotherapy, 1972, 2(2): 73-78./[3]Wissing M D, et al. Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression[J]. Oncology reports, 2014, 32(1): 419-424./[4]Kohler Z M, et al. Tilorone increases glucose uptake in vivo and in skeletal muscle cells by enhancing Akt2/AS160 signaling and glucose transporter levels[J]. Journal of Cellular Physiology, 2023, 238(5): 1080-1094.

CAS Number: 27591-97-5

Molecular Weight: 410.55

Compound Purity: 99.80

Research Area: Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Akt;Influenza Virus

• Artikelnummer: MEXHY-B1080A-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B1080A-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK