Tofimilast, CAS 185954-27-2

Product Description: Tofimilast is an inhibitor of Phosphodiesterase 4 (PDE4) with an IC50 of 0.14 μM. Tofimilast exerts its anti-inflammatory effects by inhibiting the activity of PDE4, thereby increasing intracellular levels of cAMP[1].

Applications: COVID-19-immunoregulation

Formula: C18H21N5S

References: [1]Duplantier AJ, et al. SAR of a series of 5,6-dihydro-(9H)-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-alpha]pyridines as potent inhibitors of human eosinophil phosphodiesterase. J Med Chem. 2007 Jan 25;50(2):344-9.

CAS Number: 185954-27-2

Molecular Weight: 339.46

Research Area: Inflammation/Immunology; Neurological Disease

Solubility: 10 mM in DMSO

Target: Phosphodiesterase (PDE)

• Artikelnummer: MEXHY-106137-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-106137-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK