Topiroxostat (Standard), CAS 577778-58-6

Product Description: Topiroxostat (Standard) is the analytical standard of Topiroxostat. This product is intended for research and analytical applications. Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 5.3 nM and a Ki value of 5.7 nM. Topiroxostat exhibits weak CYP3A4-inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment[1][2].

Formula: N/A

References: [1]Sato T, et al. Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [corrected]. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9./[2]Matsumoto K, et al. FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase. J Pharmacol Exp Ther. 2011 Jan;336(1):95-103.

CAS Number: 577778-58-6

Molecular Weight: N/A

Research Area: Metabolic Disease

Target: Cytochrome P450;Xanthine Oxidase

• Artikelnummer: MEXHY-14874R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-14874R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK