Topoisomerase II inhibitor 14, CAS 305343-00-4

Product Description: Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO[1].

Formula: C15H11Cl2N5

References: [1]Al-Karmalawy AA, et al. Novel fused imidazotriazines acting as promising top. II inhibitors and apoptotic inducers with greater selectivity against head and neck tumors: Design, synthesis, and biological assessments. Eur J Med Chem. 2023 Nov 5;259:115661.

CAS Number: 305343-00-4

Molecular Weight: 332.19

Compound Purity: 99.68

Research Area: cancer

Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;Topoisomerase

• Artikelnummer: MEXHY-W278582-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-W278582-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK