Trametinib, CAS 871700-17-3

Description: Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.

CAS Number: 871700-17-3

Formula: C26H23FIN5O4

Molecular Weight: 615,39

References: Wabitsch S, et al. Anti-PD-1 in Combination With Trametinib Suppresses Tumor Growth and Improves Survival of Intrahepatic Cholangiocarcinoma in Mice. Cell Mol Gastroenterol Hepatol. 2021;12(3):1166-1178.

• Artikelnummer: TGMT2125-1mL
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T2125-1mL
• Verpackungseinheit: 1 mL
• Mengeneinheit: STK