Product Description: trans-VUF25471 (Compound trans-3e) is a photoswitchable ACKR3 agonist. trans-VUF25471 binds and activates ACKR3 at 10-fold lower concentrations compared to its cis-isomer[1].
Formula: C23H29FN4O
References: [1]Sophie Bérenger, et al. Design, synthesis and pharmacological characterization of the first photoswitchable small-molecule agonist for the Atypical Chemokine Receptor 3.bioRxiv 2024.03.20.585914