Trelagliptin (succinate) (Standard), CAS 1029877-94-8

Product Description: Trelagliptin (succinate) (Standard) is the analytical standard of Trelagliptin (succinate). This product is intended for research and analytical applications. Trelagliptin (SYR-472) succinate is a potent, orally active and highly selective DPP-4 inhibitor with an IC50 of 4 nM. Trelagliptin succinate improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM)[1].

Formula: N/A

References: [1]Bhumika D Patel, et al. Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors. Eur J Med Chem. 2014 Mar 3;74:574-605./[2]Charles E Grimshaw, et al. Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism. PLoS One. 2016 Jun 21;11(6):e0157509./[3]Shiliang Li, et al. Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes. J Med Chem. 2019 Mar 14;62(5):2348-2361.

CAS Number: 1029877-94-8

Molecular Weight: N/A

Research Area: Metabolic Disease

Target: Dipeptidyl Peptidase

• Artikelnummer: MEXHY-15408AR-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15408AR-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK