Trifarotene (Standard), CAS 895542-09-3

Product Description: Trifarotene (Standard) is the analytical standard of Trifarotene. This product is intended for research and analytical applications. Trifarotene (CD5789) is a potent and selective RARγ agonist. Trifarotene (CD5789) shows ∼65-fold and ∼16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM), respectively[1].

Formula: N/A

References: [1]Etienne Thoreau, et al. Structure-based design of Trifarotene (CD5789), a potent and selective RARγ agonist for the treatment of acne. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1736-1741./[2]J Aubert, et al. Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-γ agonist trifarotene. Br J Dermatol. 2018 Aug;179(2):442-456.

CAS Number: 895542-09-3

Molecular Weight: N/A

Research Area: Inflammation/Immunology

Target: Autophagy;RAR/RXR

• Artikelnummer: MEXHY-100256R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-100256R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK