Troglitazone (Standard), CAS 97322-87-7

Product Description: Troglitazone (Standard) is the analytical standard of Troglitazone. This product is intended for research and analytical applications. Troglitazone is an orally active PPARγ agonist, with EC50s of 550 nM and 780 nM for human and murine PPARγ receptor, respectively. Troglitazone has anticancer activity, prevents and inhibits the development of type 2 diabetes.

Formula: N/A

References: [1]Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50./[2]Fujita M, et al. In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer. J Exp Clin Cancer Res. 2017 Jul 3;36(1):91./[3]Nazim UM, et al. PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux. Oncotarget. 2017 Apr 18;8(16):26819-26831./[4]Knowler WC, et al. Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program. Diabetes. 2005 Apr;54(4):1150-6.

CAS Number: 97322-87-7

Molecular Weight: N/A

Research Area: Cancer; Metabolic Disease

Target: Apoptosis;Autophagy;Ferroptosis;PPAR

• Artikelnummer: MEXHY-50935R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-50935R-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK