TYM-3-98

Product Description: TYM-3-98 is a selective inhibitor for PI3Kδ, with an IC50 of 7.1 nM. TYM-3-98 inhibits proliferationso of B-lymphoma cells. TYM-3-98 inhibits PI3K/AKT/mTOR signaling pathway through induction of apoptosis. TYM-3-98 exhibits good pahrmacokinetic characters and antitumor efficacy in mouse/rat model, without significant toxicity[1].

Formula: C28H23ClFN7O3S

References: [1]Lou SY, et al., TYM-3-98, a novel selective inhibitor of PI3Kδ, demonstrates promising preclinical antitumor activity in B-cell lymphomas. Life Sci. 2024 Jun 15;347:122662.

Molecular Weight: 592.04

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;PI3K

• Artikelnummer: MEXHY-163538-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-163538-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK