Product Description: URAT1/GLUT9-IN-1(compound 29) can inhibit both uric acid transporter 1(URAT1)(IC50=2.01 μM) and glucose transporter 9(GLUT9)(IC50=18.21 μM). URAT1/GLUT9-IN-1 exhibits favorable pharmacokinetic properties and oral bioavailability. URAT1/GLUT9-IN-1 can be uesd for gout and hyperuricemia research[1].
Formula: C23H21N3O2S2
References: [1]Shi X, et al. Discovery of a Novel Thienopyrimidine Compound as a Urate Transporter 1 and Glucose Transporter 9 Dual Inhibitor with Improved Efficacy and Favorable Druggability[J]. Journal of Medicinal Chemistry, 2024, 67(6): 5032-5052.