UU-T02, CAS 1500080-17-0

Product Description: UU-T02 is a novel potent, selective small-molecule inhibitor of β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) with a Ki of 1.36 μM[1]. UU-T02 inhibits canonical Wnt signaling and the growth of colorectal cancer cells[2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C33H33ClN4O9

References: [1]Huang Z, et al. Targeting the Tcf4 G13ANDE17 binding site to selectively disrupt β-catenin/T-cell factor protein-protein interactions. ACS Chem Biol. 2014;9(1):193-201./[2]Catrow JL, et al. Discovery of Selective Small-Molecule Inhibitors for the β-Catenin/T-Cell Factor Protein-Protein Interaction through the Optimization of the Acyl Hydrazone Moiety. J Med Chem. 2015;58(11):4678-4692.

CAS Number: 1500080-17-0

Molecular Weight: 665.09

Compound Purity: 99.63

Research Area: Cancer; Metabolic Disease

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Wnt;β-catenin

• Artikelnummer: MEXHY-117233-50
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-117233-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK