Vinpocetine (Standard), CAS 42971-09-5

Product Description: Vinpocetine (Standard) is the analytical standard of Vinpocetine. This product is intended for research and analytical applications. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders[1][2][3].

Formula: N/A

References: [1]Kye-Im Jeon et al. Vinpocetine inhibits NF-κB-dependent inflammation via an IKK-dependent but PDE-independent mechanism PNAS May 25, 2010 vol. 107 no. 21 9795-9800/[2]Patyar S, et al. Role of vinpocetine in cerebrovascular diseases. Pharmacol Rep. 2011;63(3):618-28./[3]Alexandre E. Medina Vinpocetine as a potent antiinflammatory agent PNAS June 1, 2010, Vol. 107, No. 22 9921-9922.

CAS Number: 42971-09-5

Molecular Weight: N/A

Research Area: Inflammation/Immunology; Neurological Disease; Cardiovascular Disease; Cancer

Target: IKK;Phosphodiesterase (PDE);Sodium Channel

• Artikelnummer: MEXHY-13295R-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-13295R-0
• Green Labware: Nein
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• Mengeneinheit: STK