Product Description: VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation, with an IC50 of 12.7 μM. VK-28 exhibits significant neuroprotective effects on ICV-6-OHDA. VK-28 can be used for the research of Parkinson’s disease and other neurodegenerative diseases[1].
Applications: Neuroscience-Neurodegeneration
Formula: C16H21N3O2
References: [1]Shachar DB, et al. Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats. Neuropharmacology. 2004 Feb;46(2):254-63.
CAS Number: 312611-92-0
Molecular Weight: 287.36
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Ferroptosis