Product Description: Walrycin B, an analogue of toxoflavin, is a potent SARS-CoV-2 3CLpro inhibitor with an IC50 of 0.26 μM. Walrycin B is a WalR response regulator inhibitor. Walrycin B has potent activity of inhibiting bacteria growth[1][2].
Applications: COVID-19-immunoregulation
Formula: C14H10F3N5O2
References: [1]Gotoh Y, et al. Novel antibacterial compounds specifically targeting the essential WalR response regulator. J Antibiot (Tokyo). 2010 Mar;63(3):127-34./[2]Wei Zhu, et al. Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening. bioRxiv. 2020 Aug 11:2020.07.17.207019.
CAS Number: 878419-78-4
Molecular Weight: 337.26
Compound Purity: 98.38
Research Area: Infection; Inflammation/Immunology
Solubility: DMSO : 11.5 mg/mL (ultrasonic;warming)
Target: Antibiotic;Bacterial;SARS-CoV