Product Description: XY101 is a potent, selective, metabolically stable and orally available RORγ inverse agonist with an IC50 of 30 nM and a Kd of 380 nM[1].
Applications: Cancer-programmed cell death
Formula: C25H20F7NO4S
References: [1]Zhang Y, et al. Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. J Med Chem. 2019 May 9;62(9):4716-4730.
CAS Number: 2349368-16-5
Molecular Weight: 563.48
Compound Purity: 98.88
Research Area: Cancer
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: ROR