Product Description: ZL-12A probe is a "stereoprobe "that can promote the degradation of TFIIH helicase ERCC3. ZL-12A degrades ERCC3 by covalently modifying C342[1].
Formula: C24H23N3O2
References: [1]Liu Z, et al. Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders. J Am Chem Soc. 2024 Apr 17;146(15):10393-10406.