Formulation: A solid
Purity: ≥98%
Formula Markup: C19H32O
Formula Weight: 276,5
Shelf life (days): 1460
CAS Number: 1224-92-6
Notes: 5α-Androstan-3β-ol is a steroidal androgen.{58883} It binds to the androgen receptor in a cell-free assay (IC50 = 1.7 µM) and activates the pregnane X receptor (PXR) in HepG2 cells in a reporter assay (EC50 = 0.8 µM).{58883,58884} 5α-Androstan-3β-ol also inhibits the androst-4-ene-3,17-dione hydroxylase activities of 16α- and 6β-hydroxylase but not 16β- or 7α-hydroxylase (IC50s = 70, 110, >150, and >150 µM, respectively).{58885} It decreases testis weight and sperm production in mice when administered at a dose of 30 mg/kg.{58886}