Formulation: A solid
Formal Name: S-(3-oxobutanoate) coenzyme A, trisodium salt, tetrahydrate
Formula Markup: C25H37N7O18P3S • 3Na [4H2O]
Formula Weight: 989,6
Shelf life (days): 730
Notes: Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway.{33693,33694} It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis.{33691,33692} Acetoacetyl-CoA is also an intermediate in the microbial biosynthesis of polyhydroxybutyrate.{33695}