Adrenomedullin (13-52) (human) (trifluoroacetate salt)

Formulation: A lyophilized powder

Formal Name: L-seryl-L-phenylalanylglycyl-L-cysteinyl-L-arginyl-L-phenylalanylglycyl-L-threonyl-L-cysteinyl-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-lysyl-L-α-aspartyl-L-lysyl-L-α-aspartyl-L-asparaginyl-L-valyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-lysyl-L-isoleucyl-L-seryl-L-prolyl-L-glutaminylglycyl-L-tyrosinamide, cyclic (4→9)-disulfide, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C200H308N58O59S2 • XCF3COOH

Formula Weight: 4533,1

Shelf life (days): 1460

Notes: Adrenomedullin (13-52) is a truncated form of adrenomedullin (1-52) (Item No. 24889).{40902} It induces nitric oxide-dependent relaxation of and inhibits release of angiotensin II (Item No. 17150) and endothelin-1 (Item No. 24127) from isolated rat aorta. In vivo, adrenomedullin (13-52) decreases mean arterial pressure (MAP) in spontaneously and renal hypertensive rats in a dose-dependent manner. Adrenomedullin (13-52) (10-3,000 ng per animal) reverses increases in lobar arterial pressure induced by U-46619 (Item No. 16450) in a dose-dependent manner in cats but has no effect on basal lobar arterial pressure or systemic arterial pressure.{39626} It also potentiates inflammatory edema and neutrophil accumulation in rats.{40903}

• Artikelnummer: CAY24891-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24891-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe