AMPR-22 (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-lysyl-L-lysyl-L-methionyl-L-methionyl-L-lysyl-L-lysylglycylglycyl-L-lysyl-L-phenylalanylglycyl-L-threonyl-L-phenylalanyl-L-methionyl-L-arginine, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C98H168N28O22S3 • XCF3COOH

Formula Weight: 2186,8

Shelf life (days): 1460

Notes: AMPR-22 is a synthetic antimicrobial peptide derived from the mitochondrial cation channel reactive oxygen species (ROS) modulator 1 (Romo1).{66141} It is active against S. aureus, methicillin-resistant S. aureus (MRSA), P. aeruginosa, and carbapenem-resistant P. aeruginosa with minimum bactericidal concentration (MBC) values of 2, 2, 2, and 4 µg/ml, respectively. AMPR-22 induces bacterial outer membrane permeability and ATP leakage to the extracellular space in S. aureus and P. aeruginosa in a concentration-dependent manner. It increases survival in a mouse model of sepsis induced by S. aureus when administered at a dose of 10 mg/kg.

• Artikelnummer: CAY36954-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36954-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe