Amyloid-β Precursor Protein (96-110) Peptide (cyclized) (human) (trifluoroacetate salt)

Formulation: A solid

Formal Name: N2-acetyl-L-asparaginyl-L-tryptophyl-L-cysteinyl-L-lysyl-L-arginylglycyl-L-arginyl-L-lysyl-L-glutaminyl-L-cysteinyl-L-lysyl-L-threonyl-L-histidyl-L-prolyl-L-histidinamide cyclic (3→10)-disulfide, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C81H128N32O19S2 • XCF3COOH

Formula Weight: 1918,2

Shelf life (days): 1460

Notes: Amyloid-β precursor protein (96-110) peptide (cyclized) is a synthetic peptide consisting of amino acids 96-110 of amyloid precursor peptide (APP) that is cyclized via a bridge between the cysteine residues at positions 3 and 10.{46177} It is homologous to the heparin-binding domain of human APP and inhibits binding of [125I]APP to heparin in vitro with an IC50 value of approximately 100 nM. Amyloid-β precursor protein (96-110) peptide (cyclized) inhibits neurite outgrowth induced by APP and mouse postnatal heparan sulfate proteoglycans (HSPG) in primary mouse hippocampal neurons when used at a concentration of 10 μg/ml.

• Artikelnummer: CAY27419-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 27419-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: Reinstoffe